KPV
Immune & Inflammation · 10 mg fill · Research Peptide
The C-terminal tripeptide of alpha-MSH, studied for NF-κB and MAP-kinase pathway inhibition in cell models.
Overview
KPV is the naturally occurring C-terminal tripeptide of alpha-melanocyte-stimulating hormone (Lys-Pro-Val). It retains the anti-inflammatory signaling described for the parent hormone without its pigmentation activity. Cell-culture and rodent studies report inhibition of NF-κB and MAP-kinase signaling and reduced pro-inflammatory cytokine output. No controlled human trials exist. Supplied lyophilized for in-vitro research use.
Specifications
- Sequence
- Lys-Pro-Val · α-MSH C-terminal tripeptide
- Form
- Lyophilized powder
- Vial Size
- 10 mg
- Purity
- Stated on the lot COA
- Reconstitution
- Bacteriostatic water
- Storage
- −20°C · protect from light
- Documentation
- Batch-specific COA
Research applications
- NF-κB and MAP-kinase signaling assays
- Cytokine-production cell-culture studies
- Melanocortin-fragment structure–activity research
- PepT1 transporter uptake studies
For research use only. This product is intended for laboratory and educational research purposes only. It is not made, labelled or sold as a drug, supplement or medical device, and it is not for human or veterinary consumption, diagnosis, treatment or cure of any condition.
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