5-Amino-1MQ
Metabolic · 50 mg fill · Research Peptide
A small-molecule NNMT inhibitor used as a research tool for probing nicotinamide methylation in cell culture.
Overview
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that transfers a methyl group from S-adenosylmethionine to nicotinamide. Because NNMT sits upstream of the NAD+ salvage pathway, the compound is used in vitro to probe NNMT activity and nicotinamide flux. The published record is limited and preclinical. Supplied for in-vitro research use.
Specifications
- Composition
- 5-amino-1-methylquinolinium · small-molecule NNMT inhibitor
- Form
- Lyophilized powder
- Vial Size
- 50 mg
- Purity
- Stated on the lot COA
- Reconstitution
- Bacteriostatic water
- Storage
- −20°C · protect from light
- Documentation
- Batch-specific COA
Research applications
- NNMT enzyme-inhibition assays
- Nicotinamide and NAD+ salvage-pathway research
- Methyl-donor flux studies in cell culture
- Small-molecule selectivity screening
For research use only. This product is intended for laboratory and educational research purposes only. It is not made, labelled or sold as a drug, supplement or medical device, and it is not for human or veterinary consumption, diagnosis, treatment or cure of any condition.
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